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knitting with DNA

knitting with DNA

By grabbing the ends of DNA with laser beams, one can make DNA do very unusual things. It is even possible to put a loop in a DNA molecule and slide it along a second DNA molecule, even though DNA and proteins are much too small to see with a microscope! At VU University, Amsterdam, we use so-called “optical tweezers” to grab plastic beads with a diameter of only a thousandth of a millimeter, that are visible under a microscope. The beads are caught in the focal point of a focused laser-beam. By sticking the ends of two DNA molecule to such beads, they can bend, twist and stretch the DNA anyway they like. This video demonstrates our DNA gymnastics trick.
Video Rating: 5 / 5

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6 Comments

  1. Comments  jmameren   |  Sunday, 11 July 2010 at 10:05 am

    @RobotBadger: If you can, please take a look at the December 2007 issue of the scientific journal Nature Methods, which contains the scientific publication behind this video — google for doi:10.1038/nmeth1126. That should clarify things. :-)

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  2. Comments  RobotBadger   |  Sunday, 11 July 2010 at 10:36 am

    This lacks any true proof at all. I see no phenotypic expressions, no tagging, no proteins… nothing is glowing…… This is silly.

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  3. Comments  DarkTemp0   |  Sunday, 11 July 2010 at 11:12 am

    they’re called optical tweezers :) just google them :D

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  4. Comments  benjorino   |  Sunday, 11 July 2010 at 11:42 am

    I think they use a laser beam, and it’s the momentum transfer from the photons as they enter the higher refractive index bead that allows a force to be applied to it

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  5. Comments  musicianhayd   |  Sunday, 11 July 2010 at 12:32 pm

    i’m a little confused as to how light can grab something, but cool!

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  6. Comments  marnixblomberg   |  Sunday, 11 July 2010 at 1:17 pm

    Lol
    Pretty CoOl

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